UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO (Amendment No. )(1) ------ Harvard Bioscience, Inc. - -------------------------------------------------------------------------------- (Name of Issuer) Common Stock, par value $.01 per share - -------------------------------------------------------------------------------- (Title of Class of Securities) 416906 10 5 ---------------------------------- (CUSIP Number) December 12, 2000 - -------------------------------------------------------------------------------- (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: / / Rule 13d-1(b) / / Rule 13d-1(c) /x/ Rule 13d-1(d) - ---------- (1)The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). (Continued on the following pages) (Page 1 of 5 Pages)

SCHEDULE 13G CUSIP No. 416906105 Page 2 of 5 Pages --------- - ------------------------------------------------------------------------------- (1) Names of Reporting Persons. David Green I.R.S. Identification Nos. of above persons (entities only). S.S.N. ###-##-#### - ------------------------------------------------------------------------------- (2) Check the Appropriate Box if a Member (a) / / of a Group (See Instructions) (b) / / - ------------------------------------------------------------------------------- (3) SEC Use Only - ------------------------------------------------------------------------------- (4) Citizenship or Place of Organization The Commonwealth of Massachusetts, U.S.A. - ------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power Beneficially 3,306,936 Owned by -------------------------------------------------- Each Reporting (6) Shared Voting Power Person With: None -------------------------------------------------- (7) Sole Dispositive Power 3,306,936 -------------------------------------------------- (8) Shared Dispositive Power None - ------------------------------------------------------------------------------- (9) Aggregate Amount Beneficially Owned by Each Reporting Person 3,306,936 Shares of Common Stock - ------------------------------------------------------------------------------- (10) Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) / / - ------------------------------------------------------------------------------- (11) Percent of Class Represented by Amount in Row (9) 12.9% - ------------------------------------------------------------------------------- (12) Type of Reporting Person *(See Instructions) IN - -------------------------------------------------------------------------------

STATEMENT ON SCHEDULE 13G ITEM 1. (a) Name of Issuer HARVARD BIOSCIENCE, INC. (b) Address of Issuer's Principal Executive Offices 84 OCTOBER HILL ROAD HOLLISTON, MASSACHUSETTS 01746 ITEM 2. (a) Name of Person Filing DAVID GREEN (b) Address of Principal Business Office or, if none, Residence 84 OCTOBER HILL ROAD HOLLISTON, MASSACHUSETTS 01746 (c) Citizenship THE COMMONWEALTH OF MASSACHUSETTS, U.S.A. (d) Title of Class of Securities COMMON STOCK, PAR VALUE $.01 PER SHARE (e) CUSIP Number 416906 10 5 ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO SECTIONS 240.13D-1(b) OR 240.13D-2(b) OR (c), CHECK WHETHER THE PERSON FILING IS A: NOT APPLICABLE (a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o). (b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c). (c) [ ] Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c). (d) [ ] Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8). (e) [ ] An investment adviser in accordance with section 240.13d-1(b)(1)(ii)(E); Page 3 of 5

(f) [ ] An employee benefit plan or endowment fund in accordance with section 240.13d-1(b)(1)(ii)(F); (g) [ ] A parent holding company or control person in accordance with section 240.13d-1(b)(1)(ii)(G); (h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813); (i) [ ] A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3); (j) [ ] Group, in accordance with section 240.13d-1(b)(1)(ii)(J). ITEM 4. OWNERSHIP (a) Amount beneficially owned: 3,306,936 (b) Percent of class: 12.9% (c) Number of shares as to which the person has: (i) Sole power to vote or to direct the vote: 3,306,936 (ii) Shared power to vote to direct the vote: NONE (iii) Sole power to dispose or to direct the disposition of: 3,306,936 (iv) Shared power to dispose or to direct the disposition of: NONE ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS NOT APPLICABLE If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [ ]. ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON. NOT APPLICABLE ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY. NOT APPLICABLE ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP NOT APPLICABLE Page 4 of 5

ITEM 9. NOTICE OF DISSOLUTION OF GROUP NOT APPLICABLE ITEM 10. CERTIFICATION SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. FEBRUARY 8, 2001 ------------------------------- Date /S/ DAVID GREEN ------------------------------- Signature DAVID GREEN ------------------------------- Name/Title Page 5 of 5